Test at home
A finger stick reading on a home INR meter, done in about a minute, with no trip to a lab.
Connected warfarin care
Fewer visits.
Fewer visits.
Better control.
WarfaRef links home INR testing, a patient app, and the clinician dashboard into one loop.
Built on Harvard research
Developed with clinicians affiliated with Harvard and Brigham and Women’s Hospital.
Patent pending
Original dosing and risk methodology, filed and currently under review.
Private by design
Invite only access, encrypted in transit and at rest, every action audit logged.
Atrial fibrillation
Mechanical heart valves
Deep vein thrombosis
Pulmonary embolism
Stroke prevention
Antiphospholipid syndrome
Recurrent venous thromboembolism
Warfarin works.
Managing it is the problem.
Warfarin has kept people alive for seventy years, and it still demands a blood draw, a clinic visit, and a dose change every few days. The therapy is not the burden. The loop around it is.
46.7%1
Mean time in therapeutic range at a primary care warfarin clinic.
17.5%1
Of patients reach the 70% time in range that guidelines target.
29.1%3
Record at least one INR above 4.5, a high bleeding risk reading.
6-144
Days between INR checks in routine practice, each one a trip.
One app. The whole picture.
Everything a patient needs to stay in range, from the reading to the dose change, in a single place they can check in seconds.
Home
The first thing a patient sees. Latest INR, current warfarin dose, and a running count of results logged, all in one status card, so the day starts with a fact instead of a guess.
- INR status against the therapeutic window, updated the moment a reading lands
- Current dose and schedule, set by the care team and visible at a glance
- Daily health tip drawn from warfarin-specific dietary and safety guidance
< 30s
to check status after opening the app
Data Entry
One number, submitted in seconds. Type a reading or pull one in from a connected meter over Bluetooth. Either way, it is timestamped and saved, online or off.
- Manual entry or automatic Bluetooth import from a home INR meter
- Offline-first: readings save locally and sync when the connection returns
- Every value timestamped and immutable once submitted
1
field to fill - the INR number, nothing else
Graphs
Every reading plotted against the same 2.0 to 3.0 therapeutic window, day by day or month by month, with anything abnormal flagged the moment it lands.
- Line chart with the therapeutic band drawn in, so out-of-range is visible instantly
- Toggle between daily, weekly, and monthly views
- Export a PDF report for a provider visit or insurance record
2.0-3.0
therapeutic INR window drawn on every chart
Chat
A direct line to the clinician managing the dose. Messages and images, with read receipts, so a question does not wait for the next appointment.
- Text and image messaging with the assigned care team
- Read receipts, so both sides know the message landed
- Conversation history attached to the patient record
0
voicemail messages to leave about a dose question
Visual recreation of the WarfaRef iOS app, for illustration. Not the production app.
Four points. One loop.
A reading taken at a kitchen table should reach the person adjusting the dose without a phone call. WarfaRef closes that loop, then writes the result back to the record the care team already works in.
System diagram
Closed loop
Home INR meter
Finger stick, at home
INR reading
WarfaRef app
Logs, reminders, messaging
Dosing order
Care team
Reviews and confirms dose
Care summary
Signed note
Home INR meter
Finger stick, at home
INR reading
WarfaRef app
Logs, reminders, messaging
Dosing order
Care team
Reviews and confirms dose
Signed note
Care summary
Home INR meter
Closes the loop
Patient data moving forward
Dosing guidance returning to the patient
From finger stick to confirmed dose.
Sync automatically
The result lands in the app timestamped and unedited. Nothing is keyed in by hand.
Clinical review
Dosing guidance and HAS-BLED bleeding risk scoring run server side, where they cannot be altered.
Care team confirms
A clinician approves the dose. The patient sees it the same minute, and the record updates.
The therapy is seventy years old.
The workflow does not have to be.
Take the draw out of the clinic and everything downstream can move. Fewer visits for the patient, a shorter queue for the nurse, and a dosing decision made on a reading that is hours old rather than weeks.1
Everything the care team needs, in one view.
One record per patient, assembled from readings the patient took themselves. No portal to reconcile, no fax, no transcription step.
See the whole panel at once
Every patient on warfarin, ranked by who needs attention today.
Watch the number, not the calendar
Every reading against the target window, the moment it lands.
A dose that changes by the day
Four weeks of prescribed doses at a glance, because warfarin schedules vary.
Answers where the reading arrived
Dose questions handled in the app instead of a voicemail queue.
A quarter of control, on one page
Time in range, adjustments and risk scoring, ready for the chart or a payer.
Everyone in the loop gets the same picture.
Patients
Fewer trips, and a number you actually understand.
- Test at home instead of driving to a lab every week
- See your INR against the target window, not just a figure
- Get the dose change the day it is decided
- Ask a question without waiting on a callback
Providers
The whole panel, sorted by who needs you today.
- Out-of-range readings surface at the top automatically
- HAS-BLED risk scoring computed server side and tamper resistant
- Dosing history and rationale attached to every change
- Less phone tag, and a written record of every instruction
Health systems
Anticoagulation quality you can actually report on.
- Time in therapeutic range measurable across the population
- Fewer out-of-range events reaching the emergency department
- Results written back to the EHR, not stranded in another portal
- Role based access and a complete audit trail by default
Research and validation
Built where the research is.
Origin
Harvard
WarfaRef grew out of work with clinicians and researchers affiliated with Harvard.
Clinical
Brigham and Women’s Hospital
Developed alongside anticoagulation practice at Brigham and Women’s Hospital.
IP
Patent pending
The dosing and risk methodology behind WarfaRef is filed and under review.
Evidence
Clinical validation in progress
Validation work is underway. Results will be published as they complete.
Platform safeguards
Access
Invite only provisioning, multi-factor authentication, role based access control.
Data
Encrypted at rest, TLS 1.2+ in transit, per-patient partitioning, immutable audit logging.
Clinical
Dosing guidance and risk scoring computed server side, where they cannot be altered.
See WarfaRef against your own panel.
We will walk through the clinician dashboard with your anticoagulation workflow in front of us, and show what the first ninety days of a pilot would look like.
Research, accelerator & pilot partners
